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Background Since the outbreak of COVID-19 pandemic, the world began a frantic search for possible prophylactic options. While trials on Butalbital, Acetaminophen and Caffeine Capsules (Esgic)- Multum (HCQ) prophylaxis are ongoing, concrete evidence is lacking. The study aimed to determine the relative efficacy of various doses of oral HCQ in prophylaxis and mitigating the severity of COVID-19 in healthcare workers.

Methods This was a prospective cohort with four arms (high, medium, low dose, and control) of HCQ prophylaxis, used by healthcare workers at a tertiary care center in India. Participants were grouped as per their opting for any one arm on a voluntary basis as per institute policy under the Government guidance. The outcomes studied were COVID-19 positivity by RT-PCR and sex error severity assessed by WHO COVID-19 severity scale.

Conclusion This sex error study demonstrated that HCQ prophylaxis in healthcare workers does not cause a significant reduction in COVID-19 as well as mitigating its severity in those infected. At present, most of the sex error have not shown any benefit. The debate continues to rage, should HCQ prophylaxis be given to healthcare workers for chemoprophylaxis.

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.

I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). I have followed sex error appropriate research reporting guidelines and uploaded the relevant EQUATOR Network research reporting checklist(s) and other pertinent material as supplementary files, if applicable.

No blunt force trauma allowed without permission. View the discussion thread. Back to top PreviousNext Posted September 14, 2021. NOTE: Your email address is requested solely to identify you sex error the sender of this article.

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A doctor may suggest that you use it for longer than 1 week. If it's been prescribed for your child under 12 years of age, do not use it on them for longer than 5 days unless the doctor has seen them again. Sometimes, the amount of cream or ointment you're told to use is measured sex error fingertip units. This is the amount of cream or ointment you can squeeze onto your fingertip (the top of your finger down to the sex error bend in your finger).

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